Human Recombinant Cyclophilin F | 6315

Cyclophilin F is a member of peptidyl-prolyl cis-trans isomerase family. They are highly-conserved cytoplasmic enzymes that accelerate protein folding. It is a part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.

6315 | Human Recombinant Cyclophilin F DataSheet

Biomolecule/Target: N/A

Synonyms: Human Recombinant Cyclophilin F

Alternates names: Human Recombinant Cyclophilin F, Peptidylprolyl isomerase F, PPIF, CYP3, Cyp-D.

Taglines: An immunophilin family protein catalyzing the isomerization of peptide bonds

NCBI Gene ID #: 332

NCBI Gene Symbol: BIRC5

Gene Source: Human

Accession #: O15392

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per 1 g of protein

Activity (Specifications/test method): N/A

Biological activity: Specific activity is > 250 nmoles/min/mg

Results: N/A

Binding Capacity: N/A

Unit Definition: Specific activity is defined as the amount of enzyme that cleaves 1 µmole of Suc-AAFP-pNA per minute at 25°C in Tris HCl pH 8.0 using chymotrypsin.

Molecular Weight: 21 kDa

Concentration: 1 mg/ml

Appearance: Liquid

Physical form description: 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 7.5) containing 1 mM DTT 10% glycerol.

Reconstitution Instructions: N/A

Amino acid sequence: MGSSHHHHHH SSGLVPRGSH PSFMCQAGDF TNHNGTGGKS IYGSRFPDEN FTLKHVGPGV LSMANAGPNT NGSQFFICTI KTDWLDGKHV VFGHVKEGMD VVKKIESFGS KSGRTSKKIV ITDCGQLS