Description
Peroxiredoxin-5, mitochondrial in humans is encoded by the PRDX5 gene. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. It interacts with peroxisome receptor 1. In human cells, it has been shown that PRDX5 can be addressed to mitochondria, peroxisomes, the cytosol, and the nucleus.
6321 | Human Recombinant PRDX 5 DataSheet
Biomolecule/Target: N/A
Synonyms: Human Recombinant PRDX 5
Alternates names: Peroxiredoxin 5, ACR1, AOEB116, B116, PLP, PMP20, PRDX6, PRXV, SBBI10.
Taglines: An antioxidant protein implicated in a variety of cellular responses
NCBI Gene ID #: 301291
NCBI Gene Symbol: IL-17F
Gene Source: Human
Accession #: Q5BJ95
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: Specific activity: approximately 117-136 pmole/min/µg.
Results: N/A
Binding Capacity: N/A
Unit Definition: Specific activity is defined as the amount of hydroperoxide that 1 µg of enzyme can reduce at 25°C for 1 minute.
Molecular Weight: 17 kDa
Concentration: 1 mg/ml
Appearance: Liquid
Physical form description: 1 mg/ml solution in 20 mM HEPES buffer (pH 7.4).
Reconstitution Instructions: N/A
Amino acid sequence: MAPIKVGDAI PAVEVFEGEP GNKVNLAELF KGKKGVLFGV PGAFTPGCSK THLPGFVEQA EALKAKGVQV VACLSVNDAF VTGEWGRAHK AEGKVRLLAD PTGAFGKETD LLLDDSLVSI FGNRRLKRFS MVVQDGIVKA LNVEPDGTGL TCSLAPNIIS QL.