Human recombinant UBE2D3 | 6430

UBE2D3 (UbcH5b) is an E2 (ubiquitin conjugating enzyme) that is involved in the conjugation of ubiquitin to target substrates along with E1 and E3 enzymes. The UbcH5 family (including UbcH5a and UbcH5c, having 88% and 89% sequence identity with UbcH5b respectively) are the human homologues of the Saccharomyces cerevisiae UBC4/5 family (~79% sequence identity). Members of the UbcH5 family have been implicated in a number of inflammatory and cancer pathways including the ubiquitylation of p53 and IB with the help of different E3 ligases (Hdm2 and SCF complexes respectively).

6430 | Human recombinant UBE2D3 DataSheet

Biomolecule/Target: N/A

Synonyms: Human recombinant UBE2D3

Alternates names: Ubiquitin-conjugating enzyme E2 D3, Ubiquitin-protein ligase D3, Ubiquitin carrier protein D3, Ubiquitin-conjugating enzyme E2-17 kDa 3, UBC4/5, UBCH5C, MGC5416, MGC43926, UBE2D3.

Taglines: Ubiquitin conjugating enzyme involved in conjugation of ubiquitin to target substrates.

NCBI Gene ID #: 59067

NCBI Gene Symbol: IL21

Gene Source: Human

Accession #: Q9HBE4

Recombinant: Yes

Source: N/A

Purity by SDS-PAGEs: 90%

Assay: RP-HPLC

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: Typical enzyme concentration of 100 nM - 1 mM is used for in vitro conjugation, depending on conditions.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 28.707 kDa with a His6SUMO Tag

Concentration: N/A

Appearance: Liquid

Physical form description: 75 µL of a 40 µM solution (3 nmoles) in 25 mM Tris, pH 7.5, 150 mM NaCl, 10 mM DTT and 10% glycerol.

Reconstitution Instructions: N/A

Amino acid sequence: N/A