Human recombinant UBE2R1 (CDC34) | 6436

UBE2R1 is important in the control of cell cycle and DNA replication. In association with different E3 complexes, including SCF, it has been shown to target many different substrates for ubiquitination and degradation during cell division, signal transduction, and development. UBE2R1 substrates include B-Myb, Wee1, MyoD, ATF5, p27Xic1, and p27Kip1. Additionally, substrates such as p21Cip1, E2F, cyclin E, and cyclin D are putative substrates of UBE2R1 by virtue of their SCF requirement for proteolysis. This protein is useful for in vitro ubiquitinylation reactions.

6436 | Human recombinant UBE2R1 CDC34 DataSheet

Biomolecule/Target: N/A

Synonyms: Human recombinant UBE2R1 (CDC34)

Alternates names: Human recombinant UBE2R1 (CDC34), CDC-34, Ubiquitin-conjugating enzyme E2 R1, Ubiquitin-protein ligase R1, Ubiquitin-conjugating enzyme E2-32 kDa complementing, E2-CDC34, CDC34, EC 6.3.2.19, UBC3.

Taglines: Ubiquitin conjugating enzyme involved in conjugation of ubiquitin to target substrates.

NCBI Gene ID #: 246779

NCBI Gene Symbol: IL27

Gene Source: Human

Accession #: Q8K3I6

Recombinant: Yes

Source: N/A

Purity by SDS-PAGEs:

Assay: RP-HPLC

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity:

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 27.730 kDa with His Tag.

Concentration: N/A

Appearance: Liquid

Physical form description: 75 µL of a 40 µM solution (3 nmoles) in 50 mM Tris, pH 7.5, 150 mM NaCl, 10 mM DTT and 10% glycerol.

Reconstitution Instructions: N/A

Amino acid sequence: N/A