Description
Human TRAIL protein | PRP1028 | Gentaur UK, US & Europe Distribution
Product Category: Cytology
Application: Cytokines
Product Type: Cytokines
Sequence: Amino acid sequence derived from human TRAIL isoform (P50591-1) (Val114-Gly281) was expressed.
Activity: N/A
protein Lenght: The recombinant human TRAIL consists of 168 amino acids and has a predicted molecular mass of 19.5 KDa.
Preparation: E. coli
Purity: >92% as determined by SDS-PAGE
Formulation: Lyophilized from sterile 20 mM Tris, 150 mM NaCl, pH 8.0.
Kit Component: N/A
Features & Benefits : Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method.
Molecular Weight: 19.5 KD
Usage Note: Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human TRAIL protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Storage Conditions: Lyophilized Human TRAIL proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.20% HSA or BSA) . Please prevent freeze-thaw cycles.
Shipping: The product is shipped at ambient temperature.
Background: The protein encoded by Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3.
Alternative Names: Tumor Necrosis Factor Ligand Superfamily Member 10; Apo-2 Ligand; Apo-2L; TNF-Related Apoptosis-Inducing Ligand; Protein TRAIL; CD253; TNFSF10; APO2L; TRAIL
Search Names: Tumor Necrosis Factor Ligand Superfamily Member 10; Apo-2 Ligand; Apo-2L; TNF-Related Apoptosis-Inducing Ligand; Protein TRAIL; CD253; TNFSF10; APO2L; TRAIL
Tag: TRAIL