HXK I (F67) polyclonal Antibody | BS1947

HXK I (F67) polyclonal Antibody | BS1947 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: HXK I (F67) polyclonal Antibody detects endogenous levels of HXK I protein.

Molecular Weight: ~ 102 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Hexokinase-1; Hexokinase 1; Brain form hexokinase; Hexokinase type I; HK I; HK1

Immunogen: Synthetic peptide, corresponding to amino acids 30-80 of Human HXK I.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: