Hydroxyfasudil Hydrochloride | B1559

Hydroxyfasudil is a metabolite of Fasudil (Cat. No. 1787), that acts as a potent Rho-kinase (ROCK) inhibitor [(IC₅₀ = 12 μM (ROCK1); 0.17 μM (ROCK2)]. Acts as a vasodilator.

Hydroxyfasudil is a metabolite of Fasudil (Cat. No. 1787), that acts as a potent Rho-kinase (ROCK) inhibitor [(IC₅₀ = 12 μM (ROCK1); 0.17 μM (ROCK2)]. Acts as a vasodilator.

B1559 | Hydroxyfasudil Hydrochloride DataSheet

Alternate Name/Synonyms: 5-(1, 4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one;hydrochloride; HA-1100 hydrochloride

Appearance: White solid

Formulation: N/A

CAS Number: 155558-32-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₁₄H₁₈ClN₃O₃S

Molecular Weight: 343.83

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: H₂O (>5 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A potent Rho Kinase (ROCK) inhibitor

MDL Number: MFCD06411567

PubChem CID: 11371328

SMILES: C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CNC3=O.Cl

InChi: InChI=1S/C14H17N3O3S.ClH/c18-14-12-3-1-4-13(11(12)5-7-16-14)21(19,20)17-9-2-6-15-8-10-17;/h1,3-5,7,15H,2,6,8-10H2,(H,16,18);1H

InChi Key: XWWFOUVDVJGNNG-UHFFFAOYSA-N