Hyperforin. DCHA | 2153

Displays a variety of biological activities including anti-bacterial, anti-inflammatory, anticancer and anti-angiogenic effects. Also acts as an antidepressant and anxiolytic agent. Regulates expression of the cytochrome P450 CYP3A4 and CYP2C9 and hepatic drugs metabolism. Inhibits the re-uptake of neurotransmitters in synapses (serotonin, norepinephrine, dopamine, GABA, glutamate). Also acts as a potent SIRT1 and SIRT2 inhibitor.

Hyperforin. DCHA displays a variety of biological activities including anti-bacterial, anti-inflammatory, anticancer and anti-angiogenic effects. Also acts as an antidepressant and anxiolytic agent. Regulates expression of the cytochrome P450 CYP3A4 and CYP2C9 and hepatic drugs metabolism. Inhibits the re-uptake of neurotransmitters in synapses (serotonin, norepinephrine, dopamine, GABA, glutamate). Also acts as a potent SIRT1 and SIRT2 inhibitor.

2153 | Hyperforin. DCHA DataSheet

Alternate Name/Synonyms: 5-​hydroxy-​6R-​methyl-​1R,​3,​7S-​tris(3-​methyl-​2-​butenyl)-​5S-​(2-​ methyl-​1-​oxopropyl)-​6R-​(4-​methyl-​3-​pentenyl)-​bicyclo[3.3.1]non-​ 3-​ene-​2,​9-​dione. DHCA

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 238074-03-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₅H₅₂O₄.C₁₂H₂₃N

Molecular Weight: 718.1

Cell-Permeable?: Yes

Purity: ≥97% by HPLC

Solubilities: DMSO or EtOH

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: An anti-inflammatory, anticancer and anti-angiogenic agent

MDL Number: MFCD04000098

PubChem CID: 46926346

SMILES: CC(C)C(=O)C12C(=O)C(=C(C(C1=O)(CC(C2(C)CCC=C(C)C)CC=C(C)C)CC=C(C)C)O)CC=C(C)C.C1CCC(CC1)NC2CCCCC2

InChi: InChI=1S/C35H52O4.C12H23N/c1-22(2)13-12-19-33(11)27(16-14-23(3)4)21-34(20-18-25(7)8)30(37)28(17-15-24(5)6)31(38)35(33,32(34)39)29(36)26(9)10;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h13-15,18,26-27,37H,12,16-17,19-21H2,1-11H3;11-13H,1-10H2/t27-,33+,34+,35-;/m0./s1

InChi Key: KJVNMVCMFQAPDM-DNSWOBEMSA-N