IAP polyclonal Antibody | BS60372

IAP polyclonal Antibody | BS60372 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: The intestinal alkaline phosphatase gene (ALPI) encodes a digestive brush-border enzyme, IAP (also designated ALP), which is highly upregulated during small intestinal epithelial cell differentiation. IAP, an enterocyte differentiation marker that functions to limit fat absorption, has been implicated in trans-cellular transport of chylomicrons and in chylomicron formation. At high pH, IAP removes phosphate groups from proteins and from the 5' end of DNA and RNA. Most mammals have four different IAP isozymes: placental, placental- like, intestinal and non tissue-specific. Non tissue-specific isozymes are found in liver, kidney and bone. Tissues with particularly high concentrations of IAP include the liver, bile ducts, placenta and bone.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IAP polyclonal Antibody detects endogenous levels of IAP protein.

Molecular Weight: ~ 57 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Intestinal-type alkaline phosphatase; Intestinal alkaline phosphatase; ALPI

Immunogen: A synthetic peptide corresponding to residues in Human IAP.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: