ICAM4 Antibody | 22-938

ICAM4 Antibody | 22-938 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-140 of human ICAM4 (NP_001034221.1) .

Research Area: Apoptosis, Cell Cycle, Immunology, Signal Transduction

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: HepG2

Positive Control 2: Jurkat

Positive Control 3: SW480

Positive Control 4: Mouse brain

Positive Control 5: Mouse spleen

Positive Control 6: Mouse heart

Molecular Weight: Observed: 29kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: ICAM4, intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) , CD242, LW, CD242 antigen, LW blood group protein, Landsteiner-Wiener blood group antigen a, Landsteiner-Wiener blood group glycoprotein, intercellular adhesion molecule 4, intercel

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes the Landsteiner-Wiener (LW) blood group antigen (s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW (A) /LW (B) blood group antigens is a single aa variation at position 100; Gln-100=LW (A) and Arg-100=LW (B) . Alternative splicing results in multiple transcript variants encoding distinct isoforms.