IDO1 Inhibitor I | 2745

IDO1 Inhibitor I is a potent IDO1 inhibitor that displays IC₅₀ values of 67 and 19 nM for human IDO in enzymatic activity and HeLa cell assays, respectively. It is inactive against tryptophan 2,3-dioxygenase (IC₅₀ > 10 µM).

IDO1 Inhibitor I is a potent IDO1 inhibitor that displays IC₅₀ values of 67 and 19 nM for human IDO in enzymatic activity and HeLa cell assays, respectively. It is inactive against tryptophan 2,3-dioxygenase (IC₅₀ > 10 µM).

2745 | IDO1 Inhibitor I DataSheet

Alternate Name/Synonyms: 4-amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide

Appearance: White solid

Formulation: N/A

CAS Number: 914471-09-3

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₉H₇ClFN₅O₂

Molecular Weight: 271.63

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>25 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent indoleamine 2,3-dioxygenase (IDO1) inhibitor

MDL Number: N/A

PubChem CID: 53434622

SMILES: C1=CC(=C(C=C1NC(=C2C(=NON2)N)N=O)Cl)F

InChi: InChI=1S/C9H7ClFN5O2/c10-5-3-4(1-2-6(5)11)13-9(14-17)7-8(12)16-18-15-7/h1-3,13,15H,(H2,12,16)

InChi Key: MUVQOOPKPBEAJZ-UHFFFAOYSA-N