Description
IDS Polyclonal Antibody | E-AB-19223 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: Alpha L iduronate sulfate sulfatase, Alpha-L-iduronate sulfate sulfatase, AW214631, Ids, IDS, Iduronate 2 sulfatase 14 kDa chain, Iduronate 2 sulfatase 42 kDa chain, Iduronate 2 sulfatase, Iduronate 2-sulfatase 14 kDa chain, Iduronate sulfatase, Idursulfase, MPS2, RP23-29M4.1, SIDS
Application: IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cell Biology
Background: Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. An internal proteolytic cleavage occurs to produce the mature IDS present in human liver shown to contain a 42 kDa polypeptide N-terminal to a 14 kDa polypeptide..
Concentration: 1.02 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human IDS
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A