IFI6 Antibody (N-term) [APR07950G]

IFI6 Antibody (N-term) [APR07950G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This IFI6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-34 amino acids of human IFI6 (P09912-3) .

Cellular Localisation: Mitochondrion inner membrane; Multi-pass membrane protein

Molecular Weight: 12927

Clone: Polyclonal

Gene Name: IFI6 (HGNC:4054)

Gene ID: 2537

Function: Plays a role in apoptosis, negatively regulating the intrinsinc apoptotic signaling pathway and TNFSF10-induced apoptosis (PubMed:15685448, PubMed:17823654, PubMed:26244642) . However, it has also been shown to have a pro-apoptotic activity (PubMed:27673746) . Has an antiviral activity towards hepatitis C virus/HCV by inhibiting the EGFR signaling pathway, which activation is required for entry of the virus into cells (PubMed:25757571) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Interferon alpha-inducible protein 6, Interferon-induced protein 6-16, Ifi-6-16, IFI6, G1P3