IFN-2, human recombinant | 7163

IFN -1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-R1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons. Recombinant human IFN-2 is a 19.6 kDa protein containing 174 amino acid residues.

7163 | IFN-2 human recombinant DataSheet

Biomolecule/Target: IFN-2

Synonyms: IL-28A

Alternates names: Peptidyl-prolyl cis-trans isomerase FKBP2, FKBP-13, PPIase

Taglines: Induces antiviral defense

NCBI Gene ID #: 2286

NCBI Gene Symbol: FKBP2

Gene Source: Human

Accession #: P26885

Recombinant: Yes

Source: E. Coli

Purity by SDS-PAGEs: 90%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).

Activity (Specifications/test method): N/A

Biological activity: Specific activity is > 270 nmoles/min/mg, and is defined as the amount of enzyme that cleaves 1 µmole of Suc-AAFP-pNA per minute at 25°C in Tris HCl pH 8.0 using chymotrypsin.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 13.4 kDa (122 aa, 22-142 aa)

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Acetic Acid.

Reconstitution Instructions: N/A

Amino acid sequence: MATGAEGKRK LQIGVKKRVD HCPIKSRKGD VLHMHYTGKL EDGTEFDSSL PQNQPFVFSL GTGQVIKGWD QGLLGMCEGE KRKLVIPSEL GYGERGAPPK IPGGATLVFE VELLKIERRT EL