IFN-gamma, murine recombinant | 4117

IFN- is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN- receptors are present in most immune cells, which respond to IFN- signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN- signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN- stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Recombinant murine IFN- is a 15.6 kDa protein containing 134 amino acid residues.

4117 | IFN-gamma murine recombinant DataSheet

Biomolecule/Target: IFN-gamma

Synonyms: Immune Interferon-, type II interferon, T cell interferon, MAF

Alternates names: Glutathione S-transferase Mu 2, GST4, GSTM, GSTM2-2, GTHMUS.

Taglines: A critical cytokine for innate and adaptive immunity

NCBI Gene ID #: 2946

NCBI Gene Symbol: GSTM2

Gene Source: Human

Accession #: P28161

Recombinant: Yes

Source: E. Coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: 95%

Assay #2: HPLC

Endotoxin Level: <0.1 ng/g

Activity (Specifications/test method): N/A

Biological activity: Specific activity is < 25 units/mg.

Results:

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 27.9 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized from 10 mM Na2PO4, pH 7.0 + 25 mM NaCl

Reconstitution Instructions: N/A

Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MPMTLGYWNI RGLAHSIRLL LEYTDSSYEE KKYTMGDAPD YDRSQWLNEK FKLGLDFPNL PYLIDGTHKI TQSNAILRYI ARKHNLCGES EKEQIREDIL ENQFMDSRMQ LAKLCYDPDF EKLKPEYLQA LPEMLKLYSQ FLGKQPWFLG DKITFVDFIA YDVLERNQVF EPSCLDAFPN LKDFISRFEG LEKISAYMKS SRFLPRPVFT KMAVWGNK