IFN-, human recombinant | 7164

IFN- is a type I interferon, which can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-, IFN-, and IFN-, signal through IFNAR-1/IFNAR-2 receptor complex, and exert antiviral and antiproliferative activities. IFN- exhibits about 75% sequence homology with IFN-, and contains two conserved disulfide bonds, which are necessary for full biological activity. Recombinant Human IFN- is a 19.9 kDa protein consisting of 172 amino acid residues.

7164 | IFN- human recombinant DataSheet

Biomolecule/Target: IFN-

Synonyms: IFN alpha II-1, IFNW1

Alternates names: Peptidyl-prolyl cis-trans isomerase FKBP14, FKBP22

Taglines: Exerts antiviral and antiproliferative activities

NCBI Gene ID #: 55033

NCBI Gene Symbol: FKBP14

Gene Source: Human

Accession #: Q9NWM8

Recombinant: Yes

Source: E. Coli

Purity by SDS-PAGEs: 90%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).

Activity (Specifications/test method): N/A

Biological activity: Specific activity is > 240 nmoles/min/mg, and is defined as the amount of enzyme that cleaves 1 µmole of Suc-AAFP-pNA per minute at 25°C in Tris HCl pH 8.0 using chymotrypsin.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 24.2 kDa (213 aa, 20-211 aa + NT His Tag)

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.

Reconstitution Instructions: N/A

Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MALIPEPEVK IEVLQKPFIC HRKTKGGDLM LVHYEGYLEK DGSLFHSTHK HNNGQPIWFT LGILEALKGW DQGLKGMCVG EKRKLIIPPA LGYGKEGKGK IPPESTLIFN IDLLEIRNGP RSHESFQEMD LNDDWKLSKD EVKAYLKKEF EKHGAVVNES HHDALVEDIF DKEDEDKDGF ISAREFTYKH DEL