IFN-ω polyclonal Antibody | BS60296

IFN-ω polyclonal Antibody | BS60296 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: The genes encoding type I interferons (IFNs), which include 14 IFN-α genes, 1 IFN-β gene, 1 IFN-ω (also known as IFN-α II1) gene, and a number of IFN-ω pseudogenes, are clustered on human chromosome 9. Interferons-α and -β are cytokines that are widely known to induce potent anti-viral activity. IFN-α and -β exert a variety of other biological effects, including anti-tumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-ω is antigenically different from human IFN-α, IFN-β or IFN-γ, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The Type I interferon receptor (IFN-αR) interacts with IFN-α, IFN-β and IFN-ω, and seems to be a multisubunit receptor.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IFN-ω polyclonal Antibody detects endogenous levels of IFN-ω protein.

Molecular Weight: ~ 20 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Interferon omega-1; Interferon alpha-II-1; IFNW1

Immunogen: A synthetic peptide corresponding to residues in Human IFN-ω.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: