IGF-1 Antibody [IGF1/1020] | 33-409

IGF-1 Antibody [IGF1/1020] | 33-409 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat, Rabbit

Homology: N/A

Immunogen: Full-length recombinant human IGF1 protein was used as the immunogen for the IGF-1 antibody.

Research Area: Immunology

Tested Application: Flow, IF, Neut

Application: Flow Cytometry: 0.5-1 ug/million cells in 0.1ml
Immunofluorescence: 1-2 ug/ml
Functional Activity: In-vitro neutralization of biological activity of IGF-1 (Order SAF formulation)
Optimal dilution of the IGF-1 antibody should be determined by the researcher.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Protein G affinity chromatography

Clonality: Monoclonal

Clone: IGF1/1020

Isotype: IgG1, kappa

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Concentration: 0.2 mg/mL

Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.

Alternate Name: IGF1, OTTHUMP00000195084, insulin-like growth factor 1 (somatomedin C) , insulin-like growth factor 1, IGFI, IGF1A, IBP1

User Note: Optimal dilutions for each application to be determined by the researcher

BACKGROUND: This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.