IGF 1R (phospho Tyr1165 / Tyr1166) Antibody | 79-445

IGF 1R (phospho Tyr1165 / Tyr1166) Antibody | 79-445 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: IGF-1R (Phospho-Tyr1165/Tyr1166) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1165/tyrosine 1166 (T-D-Y (p) -Y (p) -R-K) derived from Human IGF-1R .

Research Area: Phospho-Specific

Tested Application: WB, IF

Application: Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200

Specificiy: This antibody detects endogenous level of IGF-1R onlywhen phosphorylated at tyrosine 1165/tyrosine1166.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 200, 95 kDa

Validation: N/A

Isoform: N/A

Purification: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+) , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Concentration: 1 mg/mL

Storage Condition: Store antibody at -20˚C for up to one year.

Alternate Name: IGFR, CD221, IGFIR, JTK13, RAB5, Insulin-like growth factor I receptor, IGF1R, kinase IGF1R

User Note: N/A

BACKGROUND: This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.