400

IGF1R Antibody (pTyr1280)- APC/Cy7

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SKU:
400-SPC-1389D-APCCY7-GEN
Availability:
IN STOCK
NULL717.00

Description

Rabbit Anti-Human IGF1R (pTyr1280) Polyclonal

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Additional Information

Size:
100 µl
Target:
IGF1R (pTyr1280)
Conjugate:
APC/Cy7
Research Area:
Cell Signaling | Protein Phosphorylation | Tyrosine Kinases | Receptor Tyrosine Kinases | Cell Signaling | Growth Factors | Insulin and Insulin-like | Cancer | Neuroscience
Alternative Name:
IGFIRC Antibody, CD_antigen: CD221 Antibody, IGFIR Antibody, Soluble IGF1R variant 2 Antibody, CD221 Antibody, CD221 antigen Antibody, MGC142172 Antibody, Insulin-like growth factor 1 receptor beta chain Antibody, Insulin-like growth factor I recepto
Category:
Antibodies
Product Type:
Polyclonal Antibody
Immunogen:
Synthetic phospho-peptide from human IGF1R around the phosphorylation site of tyrosine 1280 (pTyr1280).
Immunogen Species:
Human
Applications:
WB
Host:
Rabbit
Isotype:
IgG
Species Reactivity:
Human, Mouse, Rat
Antibody Dilution:
WB (1:250-1:500); optimal dilutions for assays should be determined by the user.
Purification:
Peptide Affinity Purified
Storage Buffer:
PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide
Concentration:
N/A
Specificity:
Detects endogenous levels of IGF1R only when phosphorylated at tyrosine 1280 (pTyr1280).
Storage:
-20ºC
Shipping:
Blue Ice or 4ºC
Certificate of Analysis:
N/A
Cellular Localization:
Plasma Membrane, Cell Membrane, Single-Pass Type I Membrane Protein, Alphav-Beta3 Integrin-Igf-1-Igf1R Complex, Integral Component Of Plasma Membrane, Intracellular Membrane-Bounded Organelle, Membrane, Receptor Complex
Tissue Specificity:
Found as a hybrid receptor with INSR in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Expressed in a variety of tissues. Overexpressed in tumors, including melanomas, cancers of
Accession Number:
NP_000866.1
Gene ID:
3480
Swiss-Prot:
P08069
Field of Use:
For in vitro research use only.
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