IGF1R monoclonal Antibody | MB63623

IGF1R monoclonal Antibody | MB63623 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: FC, WB

Application Range: WB 1:500

Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: insulin like growth factor 1 receptor

Molecular Weight: 81 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CD221; IGFIR; IGFR; JTK13

Immunogen: Human recombinant protein fragment corresponding to amino acids 741-935 of human IGF1R (NP_000866) produced in Insect.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A