IGF2BP2 Polyclonal Antibody | E-AB-40107

IGF2BP2 Polyclonal Antibody | E-AB-40107 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Hepatocellular carcinoma autoantigen p62, IF2B2, IGF 2 mRNA binding protein 2, IGF II mRNA binding protein 2, IGF-II mRNA-binding protein 2, IGF2 mRNA-binding protein 2, Igf2bp2, IMP 2, IMP-2, IMP2, Insulin like growth factor 2 mRNA binding protein 2, Insulin-like growth factor 2 mRNA-binding protein 2, OTTHUMP00000082606, OTTHUMP00000082607, OTTHUMP00000082608, p62, VICKZ 2, VICKZ family member 2, VICKZ2

Application: IHC

Reactivity: Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Immunology, Signaling transduction

Background: RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation (By similarity). Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. Binds to beta-actin/ACTB and MYC transcripts.

Concentration: 2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant human Insulin-like growth factor 2 mRNA-binding protein 2 protein

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: IHC 1:50-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A