IGSF3 polyclonal Antibody | BS70861

IGSF3 polyclonal Antibody | BS70861 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB

Application Range: WB 1:500 - 1:2000

Background: IGSF3 (immunoglobulin superfamily, member 3), also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IGSF3 polyclonal Antibody detects endogenous levels of IGSF3 protein.

Molecular Weight: ~ 135 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Immunoglobulin superfamily member 3; IgSF3; EWI-3; EWI3; KIAA0466

Immunogen: Recombinant Protein of human IGSF3.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: