IL-17E, human recombinant | 4176E

IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulated secretion of IL-8, and induces activation of the transcription factor NK-kB in cells that express the IL-17BR receptor. Recombinant human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 145 amino acid polypeptide chains.

4176E | IL-17E, human recombinant DataSheet

Biomolecule/Target :IL-17E

Synonyms: none

Alternates names: Interleukin 17E,Interleukin-25,

Taglines: A proinflammatory cytokine produced by activated T cells

NCBI Gene ID #: 64806

NCBI Gene Symbol: IL17-E

Gene Source: Human

Accession #: Q9H293

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGE: ≥98%

Assay: SDS-PAGE

Purity: ≥98%

Assay #2: HPLC

Endotoxin Level: <0.1 ng/ug

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 33.8 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized with no additives

Reconstitution Instructions: The lyophilized IL-17E can be reconstituted in Hâ‚‚O to a concentration of 0.1 ug/ul. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans