IL-18R (M270) polyclonal Antibody | BS9268

IL-18R (M270) polyclonal Antibody | BS9268 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: IL-18 receptor (IL-18R) is a type I membrane protein present in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta and heart, and absent from brain, skeletal muscle, pancreas and kidney. IL-18R is present in Hodgkin’s disease cell lines, and does not bind IL-1α or IL-1β. The association of IL-18 to IL-18R leads to activation of NFκB. At present two subunits of IL-18R have been characterized: IL-18Rα and IL-18Rβ. IL-18Rα has been described as the ligand-binding chain and IL-18Rβ as the signal-transduction chain.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IL-18R (M270) polyclonal Antibody detects endogenous levels of IL-18R protein.

Molecular Weight: ~ 62 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CD218 antigen-like family member A; CD218a; CDw218a; CDw218a antigen; IL 1Rrp; IL-18R-1; IL-18R1; IL-1Rrp; IL1 receptor related protein; IL1 receptor-related protein; IL18R; IL18R1; IL18RA; Il18ralpha; IL1R-rp; IL1RRP; Interleukin 18 receptor 1;

Immunogen: Synthetic peptide, corresponding to amino acids 236-288 of Human IL-18R.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: