IL-27A Polyclonal Antibody | ABP58925

IL-27A Polyclonal Antibody | ABP58925 | Gentaur UK, US & Europe Distribution

Immunogen: Synthesized peptide derived from part region of human IL-27A protein at amino acid sequence of 1-50

Product Category: Protein

Application: Protein General Reagents

Product Type: Primary Antibody

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: IHC-P, ELISA

Application Note: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000) .

Clonality: Polyclonal

Isotype: Rabbit IgG

Formulation: Liquid solution

Kit Component: N/A

Concentration: 1 mg/ml

Storage Buffer: PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol as stabilizer.

Storage Instructions: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Shipping Condition: Gel pack with blue ice.

Background: The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A) . It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4 (+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4 (+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR) . IL27 (Interleukin 27) is a Protein Coding gene. Diseases associated with IL27 include Eosinophilic Granulomatosis With Polyangiitis and Visceral Leishmaniasis. Among its related pathways are IL27-mediated signaling events and Cytokine Signaling in Immune system.

Alternative Names: Interleukin-27 subunit alpha; IL-27 subunit alpha; IL-27-A; IL27-A; p28

Precaution: The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.