Description
IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes, mast cells, erythroid precursor cells and megakaryoblastic leukemia cell lines. Overexpression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkins disease. Recombinant rat IL-9 is a 14.3 kDa protein of 127 amino acid residues including 10 cysteine residues which are fully conserved between the human and murine proteins.
7103 | IL-9 Rat Recombinant DataSheet
Biomolecule/Target: IL-9
Synonyms: p40 cytokine, T-cell growth factor p40
Alternates names: Prostatropin, HBGH-2, HBGF-2, FGF-2, FGF-b.
Taglines: A regulator of a variety of hematopoietic cells
NCBI Gene ID #: 2247
NCBI Gene Symbol: FGF2
Gene Source: Human
Accession #: P09038
Recombinant: Yes
Source: Human cell expressed
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: HPLC
Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).
Activity (Specifications/test method): N/A
Biological activity: ED is typically 0.1 to 0.5 ng/mL. The specific activity was determined by the dose-dependent stimulation of the proliferation of the 3T3 cell line.
Results: 0.1 to 0.5 ng/ml
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 17 kDa, monomer, non-glycosylated
Concentration: N/A
Appearance: Lyophilized powder
Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.
Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
Amino acid sequence: N/A