IL18BP monoclonal Antibody | MB0143

IL18BP monoclonal Antibody | MB0143 | Gentaur UK, US & Europe Distribution

Host: Mouse IgG2b

Reactivity: Human

Application: WB

Application Range: WB: 1:400~1000

Background: The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine,IL18. It binds IL18,prevents the binding of IL18 to its receptor,and thus inhibits IL18-induced IFN-gamma production,resulting in reduced T-helper type 1 immune responses.This protein is constitutively expressed and secreted in mononuclear cells.Elevated level of this protein is detected in the intestinal tissues of patients with Crohn´s disease.Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of IL18BP and does not cross-react with related proteins

Molecular Weight: Predicted band size:37KDa Observed band size:37/40KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: IL18 binding protein; IL-18BP; IL18 BP; IL18 BPa; IL18BP; IL18BPa; Interleukin 18 binding protein; Interleukin-18-binding protein; MC51L 53L 54L homolog gene product; Tadekinig alfa; Tadekinig-alfa.

Immunogen: Recombinant full length Human IL18BP.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: