IL1B Polyclonal Antibody | E-AB-52116

IL1B Polyclonal Antibody | E-AB-52116 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Catabolin, H1, IL 1, IL 1 beta, IL-1 beta, IL1 BETA, IL1B, IL1B, IL1F2, Interleukin 1 beta, Interleukin-1 beta, OAF, OTTHUMP00000162031, Preinterleukin 1 beta, Pro interleukin 1 beta

Application: WB, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Metabolism, Immunology

Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Concentration: 0.7 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human IL1B

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 31 kDa

Molecular Weight(Observed): Refer to figures