BW
IL1R2 polyclonal Antibody | BS62076
- SKU:
- BW-BS62076
- Availability:
- Usually ships in 5 working days
Description
IL1R2 polyclonal Antibody | BS62076 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Rat,Mouse
Application: WB
Application Range: WB: 1:500~1:1000
Background: Non-signaling receptor for IL1A, IL1B and IL1RN. ReducesIL1B activities. Serves as a decoy receptor by competetive bindingto IL1B and preventing its binding to IL1R1. Also modulatescellular response through non-signaling association with IL1RAPafter binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secretedIL1R2 recruits secreted IL1RAP with high affinity; this complexformation may be the dominant mechanism for neutralization of IL1Bby secreted/soluble receptors.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IL1R2 polyclonal Antibody detects endogenous levels of IL1R2 protein.
Molecular Weight: ~ 45 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Interleukin-1 receptor type 2; IL-1R-2; IL-1RT-2; IL-1RT2; CD121 antigen-like family member B; CDw121b; IL-1 type II receptor; Interleukin-1 receptor beta; IL-1R-beta; Interleukin-1 receptor type II; CD121b; mIL-1R2; mIL-1RII; sIL-1R2; sIL-1RII; IL1R2; IL1RB
Immunogen: Synthetic peptide, corresponding to Human IL1R2
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: