IL31RA Antibody | 22-026

IL31RA Antibody | 22-026 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IL31RA (NP_001229568.1) .

Research Area: Apoptosis, Cell Cycle, Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: Mouse liver

Positive Control 2: Mouse heart

Positive Control 3: Mouse brain

Positive Control 4: Mouse pancreas

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 83kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: CRL, CRL3, GLM-R, GLMR, GPL, IL-31RA, PLCA2, PRO21384, hGLM-R, interleukin-31 receptor subunit alpha, IL-31 receptor subunit alpha, IL-31R subunit alpha, class I cytokine receptor, cytokine receptor-like 3, gp130-like monocyte receptor, soluble type I cytokine receptor CRL3, zcytoR17

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR) . Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.