IL37 Polyclonal Antibody | E-AB-18110

IL37 Polyclonal Antibody | E-AB-18110 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: FIL1, FIL1 zeta, FIL1(ZETA), FIL1Z, IL 1 zeta, IL 1F7, IL 1F7b (IL 1H4, IL 1H, IL 1RP1), IL 1H4, IL 1RP1, IL 1X, IL 1X protein, IL-1 zeta, IL-1F7, IL-1H, IL-1H4, IL-1RP1, IL-1X, IL-37, IL1F7 (canonical product IL 1F7b), IL1F7, IL1F7, IL1H4, IL1RP1, Interleukin 1 family member 7, interleukin 1 family, member 7 (zeta), Interleukin 1 homolog 4, Interleukin 1 related protein, Interleukin 1 superfamily z, Interleukin 1 zeta, Interleukin 37, Interleukin-1 family member 7, Interleukin-1 homolog 4, Interleukin-1 zeta, Interleukin-1-related protein, Interleukin-23

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Immunology

Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. IL37 (Interleukin 37) is a Protein Coding gene. Diseases associated with IL37 include Rheumatoid Arthritis. Among its related pathways are Innate Immune System and Toll-Like receptor Signaling Pathways. GO annotations related to this gene include cytokine activity and interleukin-1 receptor binding. An important paralog of this gene is IL36G.

Concentration: 1.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human IL37

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 24 kDa

Molecular Weight(Observed): Refer to figures