IL5RA Polyclonal Antibody | E-AB-16515

IL5RA Polyclonal Antibody | E-AB-16515 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CD125, CD125 antigen, CDw125, HSIL5R3, IL-5 receptor subunit alpha, IL-5R subunit alpha, IL-5R-alpha, IL-5RA, IL5R, IL5RA, IL5RA, Interleukin 5 Receptor alpha, Interleukin 5 Receptor alpha chain, Interleukin 5 receptor alpha subunit, Interleukin 5 receptor subunit alpha, Interleukin 5 receptor type 3, Interleukin-5 receptor subunit alpha, MGC26560

Application: WB, IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Immunology

Background: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.

Concentration: 0.9 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human IL5RA

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 48 kDa

Molecular Weight(Observed): N/A