IL6R Polyclonal Antibody | E-AB-40344

IL6R Polyclonal Antibody | E-AB-40344 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CD 126, CD126, CD126 antigen, gp80, IL 6R 1, IL 6R alpha, IL 6R, IL-6 receptor alpha chain, IL-6 receptor subunit alpha, IL-6R 1, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6Q, Il6r, IL6RA, IL6RA, IL6RQ, Interleukin 6 receptor, interleukin 6 receptor, alpha, Interleukin-6 receptor subunit alpha, Membrane glycoprotein 80, MGC30256

Application: WB, IHC

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Immunology, Stem Cells

Background: This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Human Interleukin-6 receptor subunit alpha protein

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification Method: Antigen Affinity Purification

Dilution: WB 1:1000-1:2000 IHC 1:100-1:300

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 40, 51 kDa

Molecular Weight(Observed): 80 kDa