Ilimaquinone | 2038

Cell-permeable. A marine sponge metabolite that acts as a cytoplasmic microtubule inhibitor. Induces a complete and reversible breakdown/disruption of Golgi membranes into smaller vesicular structures and blocks the association of the ADP-ribosylation factor and β-COP to the Golgi membrane. Ilimaquinone displays anticancer activity via GADD153-mediated pathway.

Ilimaquinone is a marine sponge metabolite that acts as a cytoplasmic microtubule inhibitor. Induces a complete and reversible breakdown/disruption of Golgi membranes into smaller vesicular structures and blocks the association of the ADP-ribosylation factor and β-COP to the Golgi membrane. Ilimaquinone displays anticancer activity via GADD153-mediated pathway.

2038 | Ilimaquinone DataSheet

Alternate Name/Synonyms: 3-[(Decahydro-1α,2β,4aβ-trimethyl-5-methylene-1-naphthyl)methyl]-2-hydroxy-5-methoxybenzoquinone; IQ

Appearance: Yellow solid

Formulation: N/A

CAS Number: 71678-03-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₃₀O₄

Molecular Weight: 358.47

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A cytoplasmic microtubule inhibitor.

MDL Number: MFCD00274432

PubChem CID: 72291

SMILES: CC1CCC2(C(C1(C)CC3=C(C(=O)C=C(C3=O)OC)O)CCCC2=C)C

InChi: InChI=1S/C22H30O4/c1-13-7-6-8-18-21(13,3)10-9-14(2)22(18, 4)12-15-19(24)16(23)11-17(26-5)20(15)25/h11,14,18,24H,1,6-10,12H2, 2-5H3/t14-,18+,21+,22+/m0/s1

InChi Key: JJWITJNSXCXULM-YVUMSICPSA-N