Description
IMPDH2 Polyclonal Antibody | E-AB-11330 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: IMDH2, IMP (inosine monophosphate) dehydrogenase 2, IMP dehydrogenase 2, IMP oxireductase 2, IMPD 2, IMPD2, IMPDH 2, IMPDH II, IMPDH-II, Impdh2, Inosine 5' monophosphate dehydrogenase 2, Inosine 5' phosphate dehydrogenase 2, Inosine monophosphate dehydrogenase type II, Inosine-5''-monophosphate dehydrogenase 2
Application: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Metabolism, Signal Transduction
Background: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Concentration: 0.5 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human IMPDH2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 56 kDa
Molecular Weight(Observed): N/A