INCB39110 | B1894

INCB39110 is a potent JAK1 (Janus Kinase 1) inhibitor that displays anticancer properties.

INCB39110 is a potent JAK1 (Janus Kinase 1) inhibitor that displays anticancer properties.

B1894 | INCB39110 DataSheet

Alternate Name/Synonyms: 2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(1-(3-fluoro-2-(trifluoromethyl)isonicotinoyl)piperidin-4-yl)azetidin-3-yl)acetonitrile; Itacitinib; INCB039110

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1334298-90-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₆H₂₃F₄N₉O

Molecular Weight: 553.51

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent JAK1 (Janus Kinase 1) inhibitor

MDL Number: N/A

PubChem CID: 53380437

SMILES: C1CN(CCC1N2CC(C2)(CC#N)N3C=C(C=N3)C4=C5C=CNC5=NC=N4)C(=O)C6=C(C(=NC=C6)C(F)(F)F)F

InChi: InChI=1S/C26H23F4N9O/c27-20-18(1-7-32-22(20)26(28,29)30)24(40)37-9-3-17(4-10-37)38-13-25(14-38,5-6-31)39-12-16(11-36-39)21-19-2-8-33-23(19)35-15-34-21/h1-2,7-8,11-12,15,17H,3-5,9-10,13-14H2,(H,33,34,35)

InChi Key: KTBSXLIQKWEBRB-UHFFFAOYSA-N