INF2 Antibody | 8631

INF2 Antibody | 8631 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: Predicted species reactivity based on immunogen sequence: Mouse: (100%) , Frog (71%)

Immunogen: INF2 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human INF2.

Research Area: Cell Cycle, Cancer

Tested Application: E, WB

Application: INF2 antibody can be used for Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human and rat samples. All other applications and species not yet tested.

Specificiy: INF2 Antibody is predicted to not cross-react with other INF1.

Positive Control 1: Cat. No. 1202 - A431 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 137 kDa
Observed: 160 kDa

Validation: N/A

Isoform: N/A

Purification: INF2 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: INF2 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: INF2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: INF2 Antibody: FSGS5, CMTDIE, C14orf151, C14orf173

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: INF2 is a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5