ING3 polyclonal Antibody | BS7888

ING3 polyclonal Antibody | BS7888 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IF

Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:200

Background: ING3 belongs to a family of proteins containing the plant homeodomain (PHD) finger, which includes transcription factors and proteins that regulate chromatin structure. ING3 is a component of the NuA4 histone acetyltransferase (HAT) complex and can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of ING3 has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of the ING3 gene were detected in head and neck cancers.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ING3 polyclonal Antibody detects endogenous levels of ING3 protein.

Molecular Weight: ~ 47 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Eaf 4; Eaf4; FLJ20089; ING 2; ING 3; ING2; Inhibitor of growth family member 3; Inhibitor of growth protein 3; MEAF4; p47 ING 3; p47 ING3; p47 regulator protein; p47ING3; p47ING3 protein;

Immunogen: Recombinant full length Human ING3.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: