INPP5A Antibody (C-term) [APR33128G]

INPP5A Antibody (C-term) [APR33128G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This INPP5A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 306-340 amino acids from the C-terminal region of human INPP5A.

Cellular Localisation: Cell membrane; Lipid-anchor {ECO:0000269|PubMed:8626616, ECO:0000305}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q7TNC9}

Molecular Weight: 47820

Clone: Polyclonal

Gene Name: INPP5A (HGNC:6076)

Gene ID: 3632

Function: Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1, 4, 5-trisphosphate to inositol 1, 4-bisphosphate, and inositol 1, 3, 4, 5-tetrasphosphate to inositol 1, 3, 4-trisphosphate (PubMed:8013665, PubMed:8769125, PubMed:8626616) . Plays a crucial role in the survival of cerebellar Purkinje cells (By similarity) .

Summary: Tissue Location: Predominantly expressed in heart, brain, and skeletal muscle (PubMed:8006039) . In brain; high level in Purkinje cells (PubMed:8013665) .

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Type I inositol 1, 5-trisphosphate 5-phosphatase, 5PTase, INPP5A