Insulin, human recombinant (Yeast) | 4773

Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Insulin Human Recombinant produced in Yeast is a two chain, glycosylated polypeptide chain containing 51 amino acids and having a molecular mass of 5.807 kDa. Zinc content was found to be 0.4%. Insulin is purified by proprietary chromatographic techniques.

4773 | Insulin human recombinant Yeast DataSheet

Biomolecule/Target: N/A

Synonyms: Human insulin, insulin, h-insulin, rh-insulin, recombinant human insulin, recombinant insulin, insulin

Alternates names: Fms-related tyrosine kinase 3 ligand, FLK2, STK1, CD135, Stem Cell Tyrosine Kinase 1, FLT3LG, Flt3.

Taglines: A peptide hormone central to regulating carbohydrate and fat metabolism

NCBI Gene ID #: 2322

NCBI Gene Symbol: FLT3

Gene Source: Human

Accession #: P36888

Recombinant: Yes

Source: Human 293 cell expressed

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: 98%

Assay #2: HPLC

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: ED is typically 0.2 to 0.8 ng/mL. The specific activity was determined by the dose-dependent stimulation of the proliferation of the human acute myeloid leukemia cell line OCI-AML5.

Results: 0.2 to 0.8 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 24 to 30 kDa, monomer, glycosylated

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered white lyophilized (freeze-dried) powder. The protein was lyophilized from 50mM Sodium Chloride solution.

Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.

Amino acid sequence: N/A