Insulin protease polyclonal Antibody | BS90717

Insulin protease polyclonal Antibody | BS90717 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat, zebrafish

Application: WB IHC

Application Range: WB:1:1,000-1:2,000 IHC:1:50-1:200

Background: Insulin degrading enzyme (IDE), also known as insulinase, insulin protease or insulysin, cleaves the peptide hormone insulin with consequences for insulin response and resistance. IDE is a highly conserved thiol metalloprotease with ubiquitous expression including the brain. Since its discovery, IDE has been shown to degrade a variety of bioactive peptides. Recently the finding that IDE clears intracellular and extracellular amyloid products has spurred research into the link between IDE function and human neurodegenerative disease such as Alzheimer’s.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Insulin protease polyclonal Antibody detects endogenous levels of Insulin protease protein.

Molecular Weight: 118 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Insulinase, IDE, Abeta-degrading protease, FLJ35968, Ide, IDE, Insulin protease, Insulin-degrading enzyme, Insulinase, Insulysin, OTTHUMP00000020097,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: