Involucrin polyclonal Antibody | BS90730

Involucrin polyclonal Antibody | BS90730 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Rat

Application: WB IHC FC

Application Range: WB:1:500-1:2,000 IHC:1:50-1:200 FC:1:50-1:200

Background: Involucrin is a precursor protein of the keratinocyte cornified envelope, which is formed beneath the inner surface of the cell membrane during terminal differentiation. During keratinocyte terminal differentiation, glutamine residues of involucrin become covalently cross-linked to other envelope precursors via covalent epsilon- (gamma-glutamyl) lysine bonds. Moreover, its large size allows involucrin to cross-link molecules that are separated by substantial distances in the cornified envelope. These properties allow a single involucrin molecule to form multiple cross-links, in multiple spatial planes, with other envelope precursors.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Involucrin polyclonal Antibody detects endogenous levels of Involucrin protein.

Molecular Weight: 120 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: IVL, INVO, Involucrin, IVL,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: