IQGAP1 Polyclonal Antibody | E-AB-53496

IQGAP1 Polyclonal Antibody | E-AB-53496 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: HUMORFA01, IQ motif containing GTPase activating protein 1, IQGA1, Iqgap1, KIAA0051, p195, Ras GTPase activating like protein 1, Ras GTPase-activating-like protein IQGAP1, RasGAP-like with IQ motifs, SAR1

Application: WB, IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Signal Transduction

Background: This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

Concentration: 0.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human IQGAP1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 189 kDa

Molecular Weight(Observed): Refer to figures