IRAK-1/4 Inhibitor | 9578

IRAK-1-4 Inhibitor I is an inhibitor of interleukin-1 receptor associated kinase (IRAK) with IC₅₀ values of 0.3 μM and 0.2 μM for IRAK-1 and IRAK-4, respectively. It displays IC₅₀ values >10 µM in a panel of 27 other kinases tested.

IRAK-1-4 Inhibitor I is an inhibitor of interleukin-1 receptor associated kinase (IRAK) with IC₅₀ values of 0.3 μM and 0.2 μM for IRAK-1 and IRAK-4, respectively. It displays IC₅₀ values >10 µM in a panel of 27 other kinases tested.

9578 | IRAK-1/4 Inhibitor DataSheet

Alternate Name/Synonyms: N-[1-(2-morpholin-4-ylethyl)benzimidazol-2-yl]-3-nitrobenzamide; Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor

Appearance: Yellow solid

Formulation: N/A

CAS Number: 509093-47-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₂₁N₅O

Molecular Weight: 395.41

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO ~5 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An inhibitor of interleukin-1 receptor associated kinase (IRAK)

MDL Number: N/A

PubChem CID: 11983295

SMILES: C1COCCN1CCN2C3=CC=CC=C3N=C2NC(=O)C4=CC(=CC=C4)[N+](=O)[O-]

InChi: InChI=1S/C20H21N5O4/c26-19(15-4-3-5-16(14-15)25(27)28)22-20-21-17-6-1-2-7-18(17)24(20)9-8-23-10-12-29-13-11-23/h1-7,14H,8-13H2,(H,21,22,26)

InChi Key: QTCFYQHZJIIHBS-UHFFFAOYSA-N