IRAK4 Antibody | 24-025

IRAK4 Antibody | 24-025 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human IRAK4 (NP_057207.2) .

Research Area: Signal Transduction

Tested Application: WB, IHC

Application: WB 1:500 - 1:2000
IHC 1:50 - 1:200

Specificiy: N/A

Positive Control 1: MCF7

Positive Control 2: Jurkat

Positive Control 3: Raji

Positive Control 4: U-251MG

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 55 kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: IRAK-4 Antibody: IPD1, REN64, IRAK-4, NY-REN-64, Interleukin-1 receptor-associated kinase 4, Renal carcinoma antigen NY-REN-64

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.