IRF3 Antibody, KO Validated | 13-919

IRF3 Antibody, KO Validated | 13-919 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human IRF3 (NP_001184051.1) .

Research Area: Chemokines & Cytokines, Immunology, Innate Immunity, Transcription

Tested Application: WB, IHC, ChIP

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
ChIP: 1:20 - 1:100

Specificiy: N/A

Positive Control 1: 293T

Positive Control 2: HeLa

Positive Control 3: Jurkat

Positive Control 4: HepG2

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 56kDa

Validation: Antibody is Knockout validated.

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: IRF3 Antibody: Interferon regulatory factor 3, IRF-3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.