ITGA2B polyclonal Antibody | BS7664

ITGA2B polyclonal Antibody | BS7664 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IF

Application Range: WB: 1:500~1:2000 IF: 1:50~1:200

Background: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ITGA2B polyclonal Antibody detects endogenous levels of ITGA2B protein.

Molecular Weight: ~135 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: antigen CD41; BDPLT16; BDPLT2; CD41; cd41 antigen; CD41a; cd41b; form 2; gp2b; GPalpha IIb; gpalphaiib; gpiib; GT; gta; HPA3; Integrin alpha 2b; Integrin alpha IIb; Integrin alpha-IIb light chain; Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) ; ITA2B_HUMAN; ITGA2B; ITGAB; platelet fibrinogen receptor alpha; platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex; platelet membrane glycoprotein iib; platelet specific antigen bak;

Immunogen: Recombinant full length Human ITGA2B.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: