Description
Ivermectin is an antiparasitic agent. It acts as a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptor; also modulates glutamate-GABA-activated chloride channels.
Ivermectin is an antiparasitic agent. It acts as a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptor; also modulates glutamate-GABA-activated chloride channels.
Alternate Name/Synonyms: 22,23-Dihydroavermectin B1
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 70288-86-7
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₄₈H₇₄O₁₄
Molecular Weight: 875.1
Cell-Permeable?: Yes
Purity: ³90% (B1a); ³5% (B1b)
Solubilities: DMSO (>40 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An antiparasitic agent
MDL Number: MFCD00869511
PubChem CID: 6321424
SMILES: CCC(C)C1C(CCC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C
InChi: InChI=1S/C48H74O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,19,25-26,28,30-31,33-45,49-50,52H,11,16-18,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1
InChi Key: AZSNMRSAGSSBNP-XPNPUAGNSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |