JAZF1 Antibody (N-term) [APR30826G]

JAZF1 Antibody (N-term) [APR30826G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This JAZF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-49 amino acids from the N-terminal region of human JAZF1.

Cellular Localisation: Nucleus.

Molecular Weight: 27079

Clone: Polyclonal

Gene Name: JAZF1

Gene ID: 221895

Function: Acts as a transcriptional corepressor of orphan nuclear receptor NR2C2 (PubMed:15302918) . Inhibits expression of the gluconeogenesis enzyme PCK2 through inhibition of NR2C2 activity (By similarity) . Also involved in transcriptional activation of NAMPT by promoting expression of PPARA and PPARD (By similarity) . Plays a role in lipid metabolism by suppressing lipogenesis, increasing lipolysis and decreasing lipid accumulation in adipose tissue (By similarity) . Plays a role in glucose homeostasis by improving glucose metabolism and insulin sensitivity (By similarity) .

Summary: Tissue Location: Highest expression in testis with moderate levels in colon, placenta, prostate and ovary and low levels in brain, spleen, liver and small intestine.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, FC

Dilution: WB--1:2000

Synonyms: Juxtaposed with another zinc finger protein 1, TAK1-interacting protein 27, Zinc finger protein 802, JAZF1, TIP27, ZNF802